Here is a Jon Udell interview with Phil Libin, the CEO of Evernote, Personal Outboard Brain. in which he describes the planned future of his product as a "personal memex." It's very ambitious. The interview has some relevance for anyone interested in note-taking.
I am not sure the online "solution" really is a solution.
There are other interesting interviews in the Interviews with Innovators series.
I found especially interesting the interviews with Ward Cunningham of Wiki-fame and with Jeannette Wing from Carnegie Mellon University on "computational thinking."